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Therapeutic Category

• Antibiotic, Oral Rinse
  
• Antibiotic, Topical

Use

  Dental:
  Antibacterial dental rinse; chlorhexidine is active against gram-positive and gram-negative organisms, facultative anaerobes, aerobes, and yeast
  Chip, for periodontal pocket insertion; indicated as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis; may be used as part of a periodontal maintenance program
  Medical: Skin cleanser for surgical scrub, cleanser for skin wounds, germicidal hand rinse

Usual Dosage

Oral rinse (Peridex®)
  Precede use of solution by flossing and brushing teeth, completely rinse toothpaste from mouth; swish 15 mL undiluted oral rinse around in mouth for 30 seconds, then expectorate. Caution patient not to swallow the medicine; avoid eating for 2-3 hours after treatment. (The cap on bottle of oral rinse is a measure for 15 mL.)
  When used as a treatment of gingivitis, the regimen begins with oral prophylaxis. Patient treats mouth with 15 mL chlorhexidine; swish for 30 seconds, then expectorate; this is repeated twice daily (morning and evening). Patient should have a re-evaluation followed by a dental prophylaxis every 6 months.

Dosage Forms

  Chip, for periodontal pocket insertion (PerioChip®): 2.5 mg
  Foam, topical, with isopropyl alcohol 4% (BactoShield®): 4% (180 mL)
  Liquid, topical, with isopropyl alcohol 4%:
  Dyna-Hex® Skin Cleanser: 2% (120 mL, 240 mL, 480 mL, 960 mL, 4000 mL); 4% (120 mL, 240 mL, 480 mL, 4000 mL)
  BactoShield® 2: 2% (960 mL)
  BactoShield®, Betasept®, Exidine® Skin Cleanser, Hibiclens® Skin Cleanser: 4% (15 mL, 120 mL, 240 mL, 480 mL, 960 mL, 4000 mL)
  Rinse:
  Oral (mint flavor) (Peridex®, PerioGard®): 0.12% with alcohol 11.6% (480 mL)
  Topical (Hibistat® Hand Rinse): 0.5% with isopropyl alcohol 70% (120 mL, 240 mL)
  Sponge/Brush (Hibiclens®): 4% with isopropyl alcohol 4% (22 mL)
  Wipes (Hibistat®): 0.5% (50s)