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protein G cell antibody

Posted By: mt on 2009-03-27
In Reply to: please SM TIA =) - bowser

Subject: protein G cell antibody




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Subject: Abnormal Protein S, s/l CNN and possible lipid antibody. sm

Doc says, "pt  has hx of abnormal protein S, (s/l) CNN, and possible lipid antibody,  all three.  Hx of DVT in 2001.  She had pulmonary embolus in June at which time she had Factor V difficiency.  She has multiple coagulopathies."   Any help appreciated.Thx. mmw 


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Subject: Protein S is a vitamin K–dependent anticoagulant protein, thus low levels tend to

increase the tendency for coagulation/DVT. In this regard, I agree with you.

However, maybe the elevation of protein S at the time of the DVT rules out protein S deficiency as a probable cause of the thrombotic episode. Is there any such implication? The clotting mechanism involves a complex cascade of activation events of numerous factors, and Protein S is just one cofactor for another anticoagulant protein.

Still, it would be wise to flag the doctor and let him put the final word.
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Blood work at the time of the DVT showed that she had a slightly elevated protein S.


The doctor first says slightly low...(then says) elevated protein S. Doesn't it make sense for it to be low?


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Department of State Health Services - Microbiology Lab Tests ...



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