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Protein S is a vitamin K–dependent anticoagulant protein, thus low levels tend to

Posted By: md-mt on 2005-10-24
In Reply to: Protein S - nm

Subject: Protein S is a vitamin K–dependent anticoagulant protein, thus low levels tend to

increase the tendency for coagulation/DVT. In this regard, I agree with you.

However, maybe the elevation of protein S at the time of the DVT rules out protein S deficiency as a probable cause of the thrombotic episode. Is there any such implication? The clotting mechanism involves a complex cascade of activation events of numerous factors, and Protein S is just one cofactor for another anticoagulant protein.

Still, it would be wise to flag the doctor and let him put the final word.


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    • Protein S is a vitamin K–dependent anticoagulant protein, thus low levels tend to - md-mt

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