Abnormal Protein S, s/l CNN and possible lipid antibody. sm
Posted By: mmw on 2005-09-12
In Reply to:
Subject: Abnormal Protein S, s/l CNN and possible lipid antibody. sm
Doc says, "pt has hx of abnormal protein S, (s/l) CNN, and possible lipid antibody, all three. Hx of DVT in 2001. She had pulmonary embolus in June at which time she had Factor V difficiency. She has multiple coagulopathies." Any help appreciated.Thx. mmw
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increase the tendency for coagulation/DVT. In this regard, I agree with you.
However, maybe the elevation of protein S at the time of the DVT rules out protein S deficiency as a probable cause of the thrombotic episode. Is there any such implication? The clotting mechanism involves a complex cascade of activation events of numerous factors, and Protein S is just one cofactor for another anticoagulant protein.
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